Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes
نویسندگان
چکیده
منابع مشابه
Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects
Motivation Meta-analysis is essential to combine the results of genome-wide association studies (GWASs). Recent large-scale meta-analyses have combined studies of different ethnicities, environments and even studies of different related phenotypes. These differences between studies can manifest as effect size heterogeneity. We previously developed a modified random effects model (RE2) that can...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2011
ISSN: 1471-2164
DOI: 10.1186/1471-2164-12-229